250 mg nke Triclabendazole Bolus
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Omume ọgwụ
Pharmacodynamics Triclobendazole bụ nke benzimidazole nke ọgwụ, a na-eji ya egbochi Fasciola hepatica, ma nwee mmetụta igbu egbu na Fasciola hepatica nke afọ dị iche iche.fluke ọgwụ.Mgbe etinyere ọgwụ ahụ, ọ na-egbochi usoro microtubule na ọrụ nke parasaiti, na-egbochi ntọhapụ nke nje hydrolytic proteases.Mmetụta nke triclobendazole na ikpuru dịgasị iche na ntinye uche, dị ka ndị okenye na obere mkpokọta (1 ~ 3μg / ml)
Ọgwụ ahụ ka na-adị ndụ maka awa 24, ọrụ ahụ na-ebelata nke ukwuu na ntinye uche dị elu (10-25μg / ml) maka awa 24;nnukwu mkpokọta 25-50μg / ml na-egbochi ya kpamkpam maka awa 24.Ma ọzọ mmetụta nke ikpuru.Na 10 μg / ml, a machibidoro ọrụ awa 24 niile.
Pharmacokinetics
Bioavailability nke triclobendazole dị elu.Mgbe ejiri ọnụ 10 mg/kg arọ ahụ n'ewu na atụrụ, ọgwụ plasma kacha elu ruru 15 μg/ml n'ime awa 24 ruo 36, ọkwa triclobendazole na metabolites ọbara dị elu.Ọnụ ọgụgụ kasị elu nke ọgwụ ahụ bụ 5 ruo 20 ugboro karịa nke ndị ọzọ benzimidazole anthelmintics, na nkwụsị ọkara ndụ bụ ihe dị ka awa 22.Triclobendazole bụ nke ukwuu oxidized na atụrụ na oke na sulfone na sulfoxide usoro, nke na-ejikọta na albumin ma na-anọgide na plasma ihe karịrị ụbọchị asaa.A na-ejikọta mkpokọta plasma dị elu na njikọta na albumin plasma na ogologo oge nke ihe antifascioli.Mgbe ụbọchị 10 nke nchịkwa ọgwụ na atụrụ gasịrị, ihe dịka 95% nke ọgwụ ahụ na-apụ na nsị, 2% na-apụ na mmamịrị, na-erughị 1% na mmiri ara ehi.
Omume na ojiji
Benzimidazole ọgwụ anti-fasciola.A na-ejikarị ya maka mgbochi na ọgwụgwọ nke ọrịa hepatic Fasciola na ehi na atụrụ.
Mmeghachi omume ọjọọ
Ọnweghị mmeghachi omume ọjọọ ahụla mgbe ejiri ya dịka usoro ojiji na usoro onunu siri dị
Mkpachapụ anya
(1) Enwere nkwarụ n'oge mmepụta mmiri ara ehi.
(2) Ọ na-egbu egbu nke ukwuu maka ịkụ azụ, na akpa ọgwụ fọdụrụnụ ekwesịghị imerụ isi mmiri.
(3) Ndị ọgwụ na-enwe nfụkasị ahụ kwesịrị izere imetụ ahụ́ kpọmkwem na iku ume mgbe ha na-eji ha, na-eyi uwe aka mgbe ha na-aṅụ ọgwụ, machibido iri ihe, ịṅụ ihe ọṅụṅụ na ise siga.
(4) saa aka mgbe etinyere ya
Oge mwepụ
Ụbọchị 56 maka ehi na atụrụ
Nchekwa
Chekwaa n'ebe dị n'okpuru 30 ℃.
Hebei Veyong Pharmaceutical Co., Ltd, e guzobere na 2002, emi odude ke Shijiazhuang City, Hebei Province, China, na-esote Isi Obodo Beijing.Ọ bụ nnukwu ụlọ ọrụ ọgwụ anụmanụ enwetara ikike nke GMP, yana R&D, mmepụta na ire nke API ọgwụgwọ anụmanụ, nkwadebe, nri agbakwunyere na mgbakwunye nri.Dị ka Provincial Technical Center, Veyong eguzobela usoro R&D ọhụrụ maka ọgwụ anụmanụ ọhụrụ, ma bụrụ ụlọ ọrụ mmepụta ihe ọhụrụ na teknụzụ nke mba ama ama, enwere ndị ọkachamara teknụzụ 65.Veyong nwere abụọ mmepụta bases: Shijiazhuang na Ordos, nke Shijiazhuang isi na-ekpuchi ebe 78,706 m2, na 13 API ngwaahịa gụnyere Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, na 11 nkwadebe mmepụta akara gụnyere injection, oral ngwọta, ntụ ntụ ngwọta. , premix, bolus, pesticides na disinfectant, wdg.Veyong na-enye API, ihe karịrị 100 nkwado akara aha, yana ọrụ OEM & ODM.
Veyong na-etinye aka na njikwa nke sistemụ EHS (Environment, Health & Safety), ma nweta asambodo ISO14001 na OHSAS18001.Edepụtara Veyong n'ime ụlọ ọrụ mmepụta ihe na-emepụta atụmatụ dị na Hebei Province ma nwee ike hụ na ngwaahịa na-aga n'ihu.
Veyong guzobere usoro njikwa mma zuru oke, nweta asambodo ISO9001, asambodo China GMP, asambodo Australia APVMA GMP, asambodo Ethiopia GMP, asambodo Ivermectin CEP, wee gafere nyocha US FDA.Veyong nwere ọkachamara otu ndebanye aha, ahịa na ọrụ teknụzụ, ụlọ ọrụ anyị enwetala ntụkwasị obi na nkwado site n'aka ọtụtụ ndị ahịa site n'ịdị mma ngwaahịa dị mma, ọrụ tupu ire ere na mgbe ire ere, ọrụ siri ike na sayensị.Veyong emewo ogologo okwu imekọ ihe ọnụ na ọtụtụ mba ụwa maara na-emepụta ọgwụ ụlọ ọrụ na ngwaahịa exported na Europe, South America, Middle East, Africa, Asia, wdg karịa 60 mba na mpaghara.
