Ivermectin
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Vidiyo
Ivermectin
Ivermectinbụ ọcha crystalline ntụ ntụ, enweghị isi.Ọ na-agbaze n'efu na methanol, ethanol, acetone, ethyl acetate, ọ fọrọ nke nta ka ọ ghara ịsacha ya na mmiri, yana ntakịrị hygroscopic.Ivermectin bụ ọgwụ nje nwere ọtụtụ akụkụ macrolide semisynthetic, nke kachasị nwere ivermectin B1 (Bla + B1b) nke na-erughị 95%, nke ọdịnaya Bla na-erughị 85%.
Ụkpụrụ Ọgwụ
Ivermectin nwere mmetụta inhibitory nhọrọ, site na ijikọ njikọ dị elu nke ọwa chloride na glutamate dị ka valvụ na mkpụrụ ndụ akwara na mkpụrụ ndụ akwara nke anụmanụ na-enweghị ntụpọ, nke na-eduga na mmụba nke permeability nke membranes cell na ion chloride, na-akpata hyperpolarization nke mkpụrụ ndụ akwara. ma ọ bụ mkpụrụ ndụ akwara, na-ebute mkpọnwụ ma ọ bụ ọnwụ nke nje.Ọ na-ejikọta ya na ọwa chloride nke valves ligand ndị ọzọ, dị ka neurotransmitter g-aminobutyric acid (GABA).Nhọrọ nke ngwaahịa a bụ n'ihi na ụfọdụ mammals enweghị ọwa glutamate-chloride na vivo, na avermectin nwere naanị obere mmekọrịta maka ọwa ligand-chloride mammalian.Ngwaahịa a enweghị ike ịbanye n'ihe mgbochi ụbụrụ-ọbara mmadụ.Onchocerciasis na strongyloidiasis na hookworm, ascaris, Trichuris trichiura, na Enterobius vermicularis ọrịa.
Iji
Ivermectin bụ ọgwụ eji agwọ ọtụtụ ụdị ọrịa nje.A na-eji Ivermectin agwọ ọrịa ụmụ anụmanụ nke roundworms na ectoparasites kpatara.
A na-ejikarị Ivermectin chịkwaa ikpuru na-egbu egbu n'ime eriri afọ nke anụmanụ ndị na-eri anụ.Ọrịa nje ndị a na-abanyekarị n'anụmanụ mgbe ọ na-ata nri, gafere afọ afọ, tinye ma tozuo n'ime eriri afọ, mgbe nke ahụ gasịrị, ha na-emepụta akwa na-esi n'anụmanụ pụọ n'anụmanụ ma nwee ike ịta ahịhịa ọhụrụ.Ivermectin dị irè n'igbu ụfọdụ, ma ọ bụghị ihe niile, n'ime nje ndị a. N'ime nkịta, a na-ejikarị ya eme ihe dị ka prophylaxis megide mgbu obi.
Na ọgwụgwọ ọrịa anụmanụ, a na-eji ya egbochi na ịgwọ ọrịa obi na acariasis, n'etiti ihe ngosi ndị ọzọ.Enwere ike were ya n'ọnụ ma ọ bụ tinye ya n'akpụkpọ ahụ maka ọrịa ndị dị n'èzí.A na-ejikarị Ivermectin eme ihe maka nematodes eriri afọ, lungworms, na parasitic arthropods na ehi, atụrụ, ịnyịnya, na ezì, nematodes intestinal na nkịta, ntị ntị, Sarcoptes scabiei, filariae obi, na microfilariae, na eriri afọ nematodes na ectoparasites na anụ ọkụkọ.
Nkwadebe
Ivermectin ogbugba 1% ,2% ,3.4%, 4%;
Ivermectin ngwọta ọnụ 0.08%, 0.8%, 0.2%;
Ivermectin premix;
Ivermectin bolus;
Ihe ngwọta nke Ivermectin 0.5%,1% ;
Ivermectin gel 0.4%
Hebei Veyong Pharmaceutical Co., Ltd, e guzobere na 2002, emi odude ke Shijiazhuang City, Hebei Province, China, na-esote Isi Obodo Beijing.Ọ bụ nnukwu ụlọ ọrụ ọgwụ anụmanụ enwetara ikike nke GMP, yana R&D, mmepụta na ire nke API ọgwụgwọ anụmanụ, nkwadebe, nri agbakwunyere na mgbakwunye nri.Dị ka Provincial Technical Center, Veyong eguzobela usoro R&D ọhụrụ maka ọgwụ anụmanụ ọhụrụ, ma bụrụ ụlọ ọrụ mmepụta ihe ọhụrụ na teknụzụ nke mba ama ama, enwere ndị ọkachamara teknụzụ 65.Veyong nwere abụọ mmepụta bases: Shijiazhuang na Ordos, nke Shijiazhuang isi na-ekpuchi ebe 78,706 m2, na 13 API ngwaahịa gụnyere Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, na 11 nkwadebe mmepụta akara gụnyere injection, oral ngwọta, ntụ ntụ ngwọta. , premix, bolus, pesticides na disinfectant, wdg.Veyong na-enye API, ihe karịrị 100 nkwado akara aha, yana ọrụ OEM & ODM.
Veyong na-etinye aka na njikwa nke sistemụ EHS (Environment, Health & Safety), ma nweta asambodo ISO14001 na OHSAS18001.Edepụtara Veyong n'ime ụlọ ọrụ mmepụta ihe na-emepụta atụmatụ dị na Hebei Province ma nwee ike hụ na ngwaahịa na-aga n'ihu.
Veyong guzobere usoro njikwa mma zuru oke, nweta asambodo ISO9001, asambodo China GMP, asambodo Australia APVMA GMP, asambodo Ethiopia GMP, asambodo Ivermectin CEP, wee gafere nyocha US FDA.Veyong nwere ọkachamara otu ndebanye aha, ahịa na ọrụ teknụzụ, ụlọ ọrụ anyị enwetala ntụkwasị obi na nkwado site n'aka ọtụtụ ndị ahịa site n'ịdị mma ngwaahịa dị mma, ọrụ tupu ire ere na mgbe ire ere, ọrụ siri ike na sayensị.Veyong emewo ogologo okwu imekọ ihe ọnụ na ọtụtụ mba ụwa maara na-emepụta ọgwụ ụlọ ọrụ na ngwaahịa exported na Europe, South America, Middle East, Africa, Asia, wdg karịa 60 mba na mpaghara.
