4% ogwu ogwu nke Gentamyclin sulfate
Ngosipụta
Ọdịdị:Ngwaahịa a enweghị ụcha ka ọ bụrụ mmiri mmiri na-acha odo odo ma ọ bụ na-acha akwụkwọ ndụ akwụkwọ ndụ.
Pharmacological omume:PharmacodynamicGentamycinbụ ọgwụ nje aminoglycoside nwere mmetụta antibacterial na ụdị nje bacteria dị iche iche na-adịghị mma (dị ka Escherichia coli, Klebsiella, Proteus, Pseudomonas aeruginosa, Pasteurella, Salmonella, wdg) na Staphylococcus aureus (gụnyere β-lactamase na-emepụta nje).Ọtụtụ cocci (Streptococcus pyogenes, pneumococcus, Streptococcus faecalis, wdg), bacteria anaerobic (Bacteroides ma ọ bụ Clostridium), Mycobacterium ụkwara nta, Rickettsia na fungi na-eguzogide ọgwụ a.
Pharmacokinetics:Absorption na-adị ngwa ngwa ma zuru oke mgbe ịgba ọgwụ mgbochi intramuscular gasịrị.A na-enweta ọkwa kachasị elu n'ime awa 0,5 ruo 1.Bioavailability karịrị 90% maka ntụtụ subcutaneous ma ọ bụ intramuscular.A na-ewepụ ya nke ọma site na nzacha glomerular ma na-akpata 40% ruo 80% nke ọgwụ a na-enye.Mwepụ ọkara ndụ mgbe ịgba ọgwụ mgbochi intramuscular gasịrị bụ awa 1.8 ruo 3.3 n'ime ịnyịnya, awa 2.2 ruo 2.7 na ụmụ ehi, 0.5 ruo 1.5 awa na nkịta na nwamba, 1 awa na ehi na ezì, 1 ruo 2 awa na rabbits, na 2.3 ruo 3.2 awa n'atụrụ, buffaloes, ehi, na ewu mmiri ara ehi.
Mmekọrịta ọgwụ:
(1) Nchikota nke Gentamycin na tetracycline na erythromycin nwere ike inwe mmetụta mgbochi.
(2) Na mgbakwunye na cephalosporins, dextran, diuretics nwere ike (dị ka furosemide, wdg), na erythromycin, enwere ike ịkwalite ototoxicity nke ngwaahịa a.
(3) Skeletal muscle relaxants (dị ka succinylcholine chloride, wdg) ma ọ bụ ọgwụ nwere mmetụta a nwere ike welie neuromuscular igbochi mmetụta nke HUMIRA.
Omume na ojiji
Ọgwụ nje aminoglycoside.Maka gram-adịghị mma na nje nje nje.
Usoro onunu ogwu na nchịkwa
(1) Ototoxicity.Ọ na-ebutekarị mmebi nke vestibular na ntị, nke nwere ike ịka njọ na nchịkọta nke ọgwụ ndị a na-aga n'ihu na-adabere na dose-dabere.
(2) Mmeghachi omume nfụkasị ahụ mgbe ụfọdụ.Nwamba na-enwe mmetụta karịa, mgbe niile nwere ike ime ka ọgbụgbọ, ọgbụgbọ, salivation na ataxia.
(3) Nnukwu doses nwere ike ime ka mgbochi neuromuscular conduction.Ọnwụ mberede na-emekarị mgbe mgbakasị ahụ zuru oke maka usoro ịwa ahụ na nkịta na nwamba, yana penicillin iji gbochie ọrịa.
(4) Nwere ike ime ka nephrotoxicity na-agbanwe agbanwe.
Mkpachapụ anya
(1) Enwere ike iji Gentamycin jikọtara ya na ọgwụ nje β-lactam iji gwọọ ọrịa siri ike, mana ọ gaghị ekwekọ mgbe agwakọtara na vitro.
(2) Na mgbakwunye na penicillin, ngwaahịa a nwere mmetụta synergistic na streptococci.
(3) O nwere ịda mbà n'obi iku ume na e kwesịghị ịgbanye ya n'ime intravenous.
(4) Antagonism nwere ike ime yana yana tetracycline na erythromycin.
(5) Ngwakọta na cephalosporins nwere ike ịkwalite nephrotoxicity.
Oge mwepụ
Ezi, ehi na atụrụ ụbọchị iri anọ.
Nchekwa
Akàrà na echekwara na jụụ ọchịchịrị ebiet.
Hebei Veyong Pharmaceutical Co., Ltd, e guzobere na 2002, emi odude ke Shijiazhuang City, Hebei Province, China, na-esote Isi Obodo Beijing.Ọ bụ nnukwu ụlọ ọrụ ọgwụ anụmanụ enwetara ikike nke GMP, yana R&D, mmepụta na ire nke API ọgwụgwọ anụmanụ, nkwadebe, nri agbakwunyere na mgbakwunye nri.Dị ka Provincial Technical Center, Veyong eguzobela usoro R&D ọhụrụ maka ọgwụ anụmanụ ọhụrụ, ma bụrụ ụlọ ọrụ mmepụta ihe ọhụrụ na teknụzụ nke mba ama ama, enwere ndị ọkachamara teknụzụ 65.Veyong nwere abụọ mmepụta bases: Shijiazhuang na Ordos, nke Shijiazhuang isi na-ekpuchi ebe 78,706 m2, na 13 API ngwaahịa gụnyere Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, na 11 nkwadebe mmepụta akara gụnyere injection, oral ngwọta, ntụ ntụ ngwọta. , premix, bolus, pesticides na disinfectant, wdg.Veyong na-enye API, ihe karịrị 100 nkwado akara aha, yana ọrụ OEM & ODM.
Veyong na-etinye aka na njikwa nke sistemụ EHS (Environment, Health & Safety), ma nweta asambodo ISO14001 na OHSAS18001.Edepụtara Veyong n'ime ụlọ ọrụ mmepụta ihe na-emepụta atụmatụ dị na Hebei Province ma nwee ike hụ na ngwaahịa na-aga n'ihu.
Veyong guzobere usoro njikwa mma zuru oke, nweta asambodo ISO9001, asambodo China GMP, asambodo Australia APVMA GMP, asambodo Ethiopia GMP, asambodo Ivermectin CEP, wee gafere nyocha US FDA.Veyong nwere ọkachamara otu ndebanye aha, ahịa na ọrụ teknụzụ, ụlọ ọrụ anyị enwetala ntụkwasị obi na nkwado site n'aka ọtụtụ ndị ahịa site n'ịdị mma ngwaahịa dị mma, ọrụ tupu ire ere na mgbe ire ere, ọrụ siri ike na sayensị.Veyong emewo ogologo okwu imekọ ihe ọnụ na ọtụtụ mba ụwa maara na-emepụta ọgwụ ụlọ ọrụ na ngwaahịa exported na Europe, South America, Middle East, Africa, Asia, wdg karịa 60 mba na mpaghara.