10% Enrofloxacin injection
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Vidiyo
Ihe omume ọgwụ
Enrofloxacin bụ ọgwụ nje na-egbu egbu maka anụmanụ fluoroquinolone.Maka Escherichia coli, Salmonella, Klebsiella, Brucella, Pasteurella, Actinobacillus pleuropneumoniae, Erysipelas, Proteus, Serratia marcescens, Corynebacterium pyogenes, Porter's sepsis Bacteria, Staphylococcus aureus, Mycoplasma na-adịghị ike, Mycoplasma, wdg, nwere mmetụta dị mma n'ahụ ahụ. na Streptococcus, yana mmetụta adịghị ike na nje bacteria anaerobic.Ọ nwere mmetụta antibacterial doro anya na nje bacteria nwere mmetụta.Usoro ọrụ antibacterial nke ngwaahịa a bụ igbochi DNA gyrase nke nje bacteria ma gbochie mmịgharị DNA nke nje bacteria, ndegharị na nrụzi na nchikota.Nje bacteria enweghị ike itolite na ịmụpụta nke ọma wee nwụọ.
Pharmacokinetics
10% Enrofloxacin injectionna-etinye obi gị dum ngwa ngwa na kpamkpam site na ntụtụ intramuscular.Bioavailability nke ngwaahịa a bụ 91.9% maka ezi na 82% maka ehi mmiri ara ehi.A na-ekesa ya na anụmanụ ma nwee ike ịbanye n'anụ ahụ nke ọma.Ewezuga mmiri mmiri cerebrospinal, ntinye ọgwụ n'ihe fọrọ nke nta ka ọ bụrụ anụ ahụ niile dị elu karịa na plasma.Metabolism nke imeju na-abụkarị iji wepụ otu ethyl nke mgbanaka 7-piperazine iji mepụta ciprofloxacin, na-esote oxidation na njikọ glucuronic acid.A na-esi na akụrụ pụta nke ọma (site na renal tubular secretion na glomerular filtration), na 15% ~ 50% na-esi na mmamịrị n'ụdị mbụ ya.Mwepụ ọkara ndụ dịgasị iche iche n'etiti ụdị anụmanụ dị iche iche na ụzọ nchịkwa dị iche iche.Mwepụ ọkara ndụ mgbe ịgba ọgwụ intramuscular gasịrị bụ awa 5.9 maka ehi, awa 9.9 maka ịnyịnya, awa 1.5 ruo 4.5 maka atụrụ, na awa 4.6 maka ezì.
Mmekọrịta
(1)10% ọgwụ mgbochi nke EnrofloxacinA na-eji ya na aminoglycosides ma ọ bụ penicillin sara mbara, nke nwere mmetụta synergistic.
(2) ion dị arọ metal dị ka Ca2+, Mg2+, Fe3+ na Al3+ nwere ike chelate na ngwaahịa a ma na-emetụta absorption.
(3) Mgbe ejikọtara ya na theophylline na caffeine, ọ nwere ike ibelata ọnụego njikọ protein plasma, na-abawanye mkpokọta theophylline na caffeine n'ime ọbara n'ụzọ na-ezighi ezi, na ọbụna ịkpata mgbaàmà nke nsị theophylline.
(4) Ngwaahịa a nwere mmetụta nke inhibiting imeju ọgwụ enzymes, nke nwere ike ibelata mkpochapụ ọnụego nke ọgwụ tumadi metabolized na imeju na-abawanye ọbara ọgwụ ịta.
Ọrụ na ojiji
Fluoroquinolone ọgwụ nje.A na-eji ya maka ọrịa nje na ọrịa mycoplasma na anụ ụlọ na anụ ọkụkọ
Usoro onunu ogwu na nchịkwa
Intramuscular injection: otu dose, kwa 1kg arọ ahụ, 0.025ml maka ehi, atụrụ, na ezi;0.025 ~ 0.05ml maka nkịta, nwamba na oke bekee.Jiri 1 ruo 2 ugboro n'ụbọchị maka 2 ruo 3 ụbọchị.
Mmeghachi omume ọjọọ
(1) Mmebi nke cartilage na ụmụ anụmanụ na-eto eto, na-emetụta ọkpụkpụ ọkpụkpụ ma na-akpata claudication na mgbu.
(2) Mmeghachi omume nke usoro nri nri gụnyere vomiting, enweghị agụụ, na afọ ọsịsa.
(3) Mmeghachi omume akpụkpọ ahụ gụnyere erythema, itching, urticaria na photosensitivity.
(4) Mmeghachi omume nfụkasị ahụ, ataxia, na ọdịdọ na-ahụ mgbe ụfọdụ na nkịta na nwamba.
Hebei Veyong Pharmaceutical Co., Ltd, e guzobere na 2002, emi odude ke Shijiazhuang City, Hebei Province, China, na-esote Isi Obodo Beijing.Ọ bụ nnukwu ụlọ ọrụ ọgwụ anụmanụ enwetara ikike nke GMP, yana R&D, mmepụta na ire nke API ọgwụgwọ anụmanụ, nkwadebe, nri agbakwunyere na mgbakwunye nri.Dị ka Provincial Technical Center, Veyong eguzobela usoro R&D ọhụrụ maka ọgwụ anụmanụ ọhụrụ, ma bụrụ ụlọ ọrụ mmepụta ihe ọhụrụ na teknụzụ nke mba ama ama, enwere ndị ọkachamara teknụzụ 65.Veyong nwere abụọ mmepụta bases: Shijiazhuang na Ordos, nke Shijiazhuang isi na-ekpuchi ebe 78,706 m2, na 13 API ngwaahịa gụnyere Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, na 11 nkwadebe mmepụta akara gụnyere injection, oral ngwọta, ntụ ntụ ngwọta. , premix, bolus, pesticides na disinfectant, wdg.Veyong na-enye API, ihe karịrị 100 nkwado akara aha, yana ọrụ OEM & ODM.
Veyong na-etinye aka na njikwa nke sistemụ EHS (Environment, Health & Safety), ma nweta asambodo ISO14001 na OHSAS18001.Edepụtara Veyong n'ime ụlọ ọrụ mmepụta ihe na-emepụta atụmatụ dị na Hebei Province ma nwee ike hụ na ngwaahịa na-aga n'ihu.
Veyong guzobere usoro njikwa mma zuru oke, nweta asambodo ISO9001, asambodo China GMP, asambodo Australia APVMA GMP, asambodo Ethiopia GMP, asambodo Ivermectin CEP, wee gafere nyocha US FDA.Veyong nwere ọkachamara otu ndebanye aha, ahịa na ọrụ teknụzụ, ụlọ ọrụ anyị enwetala ntụkwasị obi na nkwado site n'aka ọtụtụ ndị ahịa site n'ịdị mma ngwaahịa dị mma, ọrụ tupu ire ere na mgbe ire ere, ọrụ siri ike na sayensị.Veyong emewo ogologo okwu imekọ ihe ọnụ na ọtụtụ mba ụwa maara na-emepụta ọgwụ ụlọ ọrụ na ngwaahịa exported na Europe, South America, Middle East, Africa, Asia, wdg karịa 60 mba na mpaghara.
