0.2% IVERMECTIN DRENCH
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Pharmacological omume
Ivermectintumadi nwere ezigbo anthelmintic mmetụta na nematodes na elu arthropods na vivo.Usoro anthelmintic ya bụ ịkwalite ntọhapụ nke γ-aminobutyric acid (GABA) site na neurons presynaptic, si otú ahụ mepee ọwa chloride mgbasa ozi GABA.Ivermectin bụkwa nhọrọ dị elu na njikọ dị elu maka ọwa glutamate-mediated chloride dị nso na saịtị GABA-mediated na akwara invertebrate na sel muscle, si otú ahụ na-etinye aka na nnyefe mgbaàmà n'etiti akwara neuromuscular na izu ike ma na-akpọnwụ parasaiti ahụ, na-akpata ọnwụ parasite ma ọ bụ ịchụpụ ya na sel anụ ahụ. ahu.Ndị inhibitory interneurons na excitatory motoneurons nke C. elegans bụ ebe ha na-eme ihe, ebe saịtị nke arthropods na-arụ ọrụ bụ nkwụsị nke neuromuscular.Ọ na-adịkwa irè megide arthropods, dị ka ikpuru ijiji, àjà, na kịta.okenye Coronaria dentata na ụmụ nje ndị na-eto eto na ezì, dịkwa oke irè maka Trichinella spiralis na eriri afọ (adịghị arụ ọrụ maka intramuscular Trichinella spiralis), ma nweekwa mmetụta dị mma na nchịkwa ọbara ezì na Sarcoptes scabiei.Ọ naghị arụ ọrụ megide trematodes na tapeworms.
Pharmacokinetics
The pharmacokinetics nkeivermectindịgasị iche iche dabere n'ụdị anụmanụ, ụdị usoro onunu ogwu, na ụzọ nchịkwa.Ọdịiche dị n'ahụ maka ịgba ọgwụ subcutaneous dị elu karịa nke nchịkwa ọnụ, mana nchịkwa ọnụ na-abanye ngwa ngwa karịa ntụtụ subcutaneous.Mgbe nnabata, enwere ike kesaa ya nke ọma na ọtụtụ anụ ahụ, mana ọ naghị adị mfe ịbanye n'ime mmiri cerebrospinal.Ọnụ ọgụgụ pụtara ìhè nke nkesa na atụrụ na ezì bụ 4.6 na 4 L / kg, n'otu n'otu.Ọ nwere ogologo ndụ ọkara ndụ n'ọtụtụ anụmanụ, 2 ruo 7 na ụbọchị 0,5 na atụrụ na ezì, n'otu n'otu.Ngwaahịa a bụ metabolized na imeju, tumadi hydroxylated na atụrụ, na tumadi methylated na ezi.A na-apụkarị ya na nsị na ihe na-erughị 5% na-apụ apụ na-agbanweghi agbanwe ma ọ bụ dị ka metabolites na mmamịrị.N'ime dams na-enye nwa ara, 5% nke dose ahụ na-apụ na mmiri ara ehi.
Mmekọrịta ọgwụ
Iji otu oge na diethylcarbamazine nwere ike mepụta encephalopathy siri ike ma ọ bụ na-egbu egbu.
Omume na ojiji
Ọgwụ antiparasitic macrolide.A na-eji ya maka njikwa nematode, acariasis na ọrịa ụmụ ahụhụ na-efe efe na atụrụ na ezì.
Usoro onunu ogwu na nchịkwa
Ọnụ: otu dose, 0.1 ml maka atụrụ na 0.15 ml maka ezi kwa 1 n'arọ nke arọ ahụ.
Mmeghachi omume ọjọọ
Ọnweghị mmeghachi omume ọjọọ ahụla mgbe ejiri ya dabere na ojiji na usoro onunu a kapịrị ọnụ.
Mkpachapụ anya
(1) Ọ bụ contraindicated n'oge lactation.
(2) Ekwesịrị iji nlezianya mee ya na ịgha mkpụrụ n'ime ụbọchị 45 mbụ nke ime ime.
(3) Ivermectin shrimp, azụ na ihe ndị dị n'ime mmiri na-egbu egbu nke ukwuu, na nkwakọ ngwaahịa na arịa ọgwụ ndị fọdụrụ agaghị emetọ isi mmiri.
Oge iwepụ: ụbọchị 35 maka atụrụ na ụbọchị 28 maka ezi.
Oge mwepụ
Ụbọchị 35 maka atụrụ na ụbọchị 28 maka ezi.
Hebei Veyong Pharmaceutical Co., Ltd, e guzobere na 2002, emi odude ke Shijiazhuang City, Hebei Province, China, na-esote Isi Obodo Beijing.Ọ bụ nnukwu ụlọ ọrụ ọgwụ anụmanụ enwetara ikike nke GMP, yana R&D, mmepụta na ire nke API ọgwụgwọ anụmanụ, nkwadebe, nri agbakwunyere na mgbakwunye nri.Dị ka Provincial Technical Center, Veyong eguzobela usoro R&D ọhụrụ maka ọgwụ anụmanụ ọhụrụ, ma bụrụ ụlọ ọrụ mmepụta ihe ọhụrụ na teknụzụ nke mba ama ama, enwere ndị ọkachamara teknụzụ 65.Veyong nwere abụọ mmepụta bases: Shijiazhuang na Ordos, nke Shijiazhuang isi na-ekpuchi ebe 78,706 m2, na 13 API ngwaahịa gụnyere Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, na 11 nkwadebe mmepụta akara gụnyere injection, oral ngwọta, ntụ ntụ ngwọta. , premix, bolus, pesticides na disinfectant, wdg.Veyong na-enye API, ihe karịrị 100 nkwado akara aha, yana ọrụ OEM & ODM.
Veyong na-etinye aka na njikwa nke sistemụ EHS (Environment, Health & Safety), ma nweta asambodo ISO14001 na OHSAS18001.Edepụtara Veyong n'ime ụlọ ọrụ mmepụta ihe na-emepụta atụmatụ dị na Hebei Province ma nwee ike hụ na ngwaahịa na-aga n'ihu.
Veyong guzobere usoro njikwa mma zuru oke, nweta asambodo ISO9001, asambodo China GMP, asambodo Australia APVMA GMP, asambodo Ethiopia GMP, asambodo Ivermectin CEP, wee gafere nyocha US FDA.Veyong nwere ọkachamara otu ndebanye aha, ahịa na ọrụ teknụzụ, ụlọ ọrụ anyị enwetala ntụkwasị obi na nkwado site n'aka ọtụtụ ndị ahịa site n'ịdị mma ngwaahịa dị mma, ọrụ tupu ire ere na mgbe ire ere, ọrụ siri ike na sayensị.Veyong emewo ogologo okwu imekọ ihe ọnụ na ọtụtụ mba ụwa maara na-emepụta ọgwụ ụlọ ọrụ na ngwaahịa exported na Europe, South America, Middle East, Africa, Asia, wdg karịa 60 mba na mpaghara.
